Somatically acquired genetic alterations in flat colorectal neoplasias
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چکیده
منابع مشابه
Somatically acquired hypomethylation of IGF2 in breast and colorectal cancer
The imprinted insulin-like growth factor 2 (IGF2) gene is expressed predominantly from the paternal allele. Loss of imprinting (LOI) associated with hypomethylation at the promoter proximal sequence (DMR0) of the IGF2 gene was proposed as a predisposing constitutive risk biomarker for colorectal cancer. We used pyrosequencing to assess whether IGF2 DMR0 methylation is either present constitutiv...
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ژورنال
عنوان ژورنال: International Journal of Cancer
سال: 1998
ISSN: 0020-7136,1097-0215
DOI: 10.1002/(sici)1097-0215(19980729)77:3<366::aid-ijc10>3.0.co;2-6